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Lack of intracellular replication of M. tuberculosis and M. bovis BCG caused by delivering bacilli to lysosomes in murine brain microvascular endothelial cells

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Figure

Figure 1: Both MtbBCG in BMECs. Mouse BMECs were infected withmembrane-bound vacuoles
Figure 2: Confocal microscopy and cell viability assays demonstrate absence of cytotoxicity in infected BMECs
Figure 3: MtbInfections were performed in triplicate and experiments repeated two times
Figure 4: Both Mtbfluorescent - and BCG-CVs retain Rab7 and LAMP2 together over time. Microscopic examination of Rab7 and LAMP2 co-localization with Mtb- and BCG-CVs in BMECs and J774A.1 cells
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