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Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling

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Academic year: 2020

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Figure

Fig. 1 Correlation between chronological age and age predicted byDNA methylation-based predicted age in two independent cohorts.a GTP cohort (n = 393)
Fig. 2 Cumulative lifetime stress is associated with epigenetic age acceleration in a highly traumatized human cohort derived from the Gradyassociated with epigenetic age acceleration (was regressed on cumulative lifetime stress (Life Stress) after adjusti
Fig. 4 Glucocorticoid receptor activation regulates the expression ofThe dotted red line represents the corrected level of statisticalsignificance (q = 5 × 10genes with transcription start sites (TSS) near epigenetic clock CpGs.Gene TSS near epigenetic clo

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