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The proinflammatory cytokines IL 1β and TNF α induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2 ETS1 pathway

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Figure

Figure 1Increased Synoviolin (SYN) expression in the synovial fibroblasts from collagen-induced arthritis (CIA) miceIncreased Synoviolin (SYN) expression in the synovial fibroblasts from collagen-induced arthritis (CIA) mice
Figure 2Figure 3
Figure 4
Figure 5SYN transcription, as indicated by the finding that the specificinhibitors against Erk, but not JNK and p38, block SYN expres-
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