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Balancing of ephrin/Eph forward and reverse signaling as the driving force of adaptive topographic mapping

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Academic year: 2020

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Figure

Fig. 1. A single-constraint model of topographic axonal mapping. (profiles, according to its topographic origin
Fig. 2. Basic performance of the model. (derived guidance cue gradients without other terminals, as indicated by Gnothing but 25 topographically ordered terminals, the probing terminal detects Gterminal overlap are causing repulsion, which is the smaller t
Fig. 3. Topographic and robust mapping. (final positions of 200 randomly seeded fibers along the a/p axis asfunction of n/t origin
Fig. 4. Single-cue stripe assays suggest monofunctional action of guidance cues. Stripe assays simulated with the present monofunctionalavoiding 16model based on forward signaling, all fibers avoid high ligand values (red: Lpredicted, with nasals preferrin
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