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RNAi mediated CD40 CD154 interruption promotes tolerance in autoimmune arthritis

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Figure

Figure 1 Knockdown of CD40 reduces allogenicity in DCs. DBA-derived DCs were cultured as described in Materials and methods
Figure 2 In vivo immunomodulation by administration of CD40 siRNA. a) and b): CII-specific T cell responses by CD40 siRNA
Figure 4 Attenuated disease development by CD40 siRNA. DBA
Figure 5 Histological changes in CIA mice after treatment with CD40 siRNAThe joints from the mice treated with CD40 siRNA b) change was scored

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