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The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4

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Figure

Figure 2. TRAM interacts directly
Figure 4. TRAM interaction with TRAF6 mediates NF-�determinations performed in three independent experiments
Figure 5. Expression of TRAM E183A inhibits TLR4-mediated activa-tion of NF-stably expressing TLR4 and MD2, were transiently transfected withTK-Renilla and (A) NF-porter constructs in conjunction with indicated amounts of TRAME183A (1–80 ng) for 24 h
Figure 7. TRAM association with TRAF6 is required for TLR4-induced proinflammatoryresponses.***results of three independent experiments performed in triplicate
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