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Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS

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Academic year: 2020

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Figure

Figure 1Study of B cells in CSF of MS patients with and without OCMBs. Representative dot plots showing CD19age of CD19(A) Both M+ MS and M– MS OCMBs showed a higher percent-+ cells in CSF when compared with the control group  (P < 0.0001)
Figure 3Study of OCMB specificity. The presence of total IgM bands (T) and of oligoclonal IgM reacting against PC, phosphatidylethanolamine (PEA), phosphatidylinositol (PI), phosphatidylserine (PS), sphingomyelin (SP), gangliosides (GA), sulphatides (SU),
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