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Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy

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Academic year: 2020

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Figure

Figure 1: Identification of androgen-responsive miRNAs in PCa cells. (A) Expression profile of microRNAs in LNCaP cells with androgen-starved for 72 h and treated with 10 nM DHT at different time point
Figure 2: miR-135a directly targets RBAK and MMP11 in PCa cells. (four open-access softwares, including TargetScan, miRanda, miRwalk, and starBase
Figure 3: MiR-135a inhibits cell proliferation and cell cycle by targeting and suppressing RBAK
Figure 4: MiR-135a induced apoptosis of PCa cells by targeting and suppressing RBAK. (performed with flow cytometer
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