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Investigation into the role of the germline epigenome in the transmission of glucocorticoid programmed effects across generations

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Academic year: 2020

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Figure

Fig. 1 Experimental design and phenotype. a Experimental design. b Placenta and pup weight at e19.5 (n = 129 vehicle (Veh) and 120 Dex)
Fig. 2 DNA methylation in F1 sperm is unaffected by Dex treatment. a Pearson correlation heatmaps with hierarchical clustering for 5mCdatasets from sperm from offspring in which the mother had been exposed to dexamethasone (D) or vehicle controls (V) as we
Fig. 3 Small RNA expression in the F1 sperm is unaffected by Dex treatment.expression
Fig. 4 Dex treatment does not induce detectable changes in histone methylation.H3 IP. Samples clearly cluster by histone mark but do not cluster by Veh vs Dex for any histone mark

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