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Pyruvate Dependent Changes in Neutrophil Amino and Alpha Keto Acid Profiles or Immunity: Which Mechanisms Are Involved?

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Table 1. Content of free amino acids [10–16 Mol] and α-keto acids [10–17 Mol] per neutrophil (PMN, mean ± standard deviation [SD]; n = 10) and their intracellular concentrations based on the mean neutrophil cell volume (NCV) [μMol/l, mean ± SD; n = 10]
Figure 1. Effects of pyruvate (1 mM, incubated for 120 min) after a 10 min pre-incubation either with L- NAME (1 mM), SNAP (100 µM), DON (100 µM), beta-Ala (10 mM) or DFMO (1 mM) on free intracellular α-ketoglutarate, pyruvate and α-ketobutyrate concentrat
Figure 4. Effects of pyruvate (1 mM, incubated for 120 min) after a 10 min pre-incubation either with L- NAME (1 mM), SNAP (100 µM), DON (100 µM), beta-Ala (10 mM) or DFMO (1 mM) on free intracellular basic amino acid concentrations (ornithine, arginine, c
Figure 7. Effects of pyruvate (1 mM, incubated for 120 min) after a 10 min pre-incubation either with L- NAME (1 mM), SNAP (100 µM), DON (100 µM), beta-Ala (10 mM) or DFMO (1 mM) on free intracellular neutral amino acid concentrations (serine, glycine) in
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