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The putative oncotarget CSN5 controls a transcription- uncorrelated p53-mediated autophagy implicated in cancer cell survival under curcumin treatment

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Academic year: 2020

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Figure

Figure 1: The effect of curcumin on CSN5 and p53. (A) Representative Western blot images in HepG2 cells treated with curcumin for 6 h, etoposide for 12 h, 5-FU for 12 h or cisplatin for 12 h
Figure 2: Curcumin-induced autophagy correlates to p53. (A) Representative Western blot images in HepG2 cells treated with 30 μM curcumin for 2, 4, 6 and 8 h, or 7.5, 15, 30 and 60 μM curcumin for 6 h
Figure 3: Curcumin controls p53 to induce autophagy uncorrelated to its transcriptional activity
Figure 4: p53-controlled autophagy promotes cancer cell survival under curcumin treatment
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