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Genetic mutations associated with metastatic clear cell renal cell carcinoma

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Figure

Figure 1: Molecular heterogeneity among tumor cells of the same patient. DNA and RNA were extracted from primary tumor (PT), tumor extension (TE), and lymphatic metastases (LM) of a stage-4 CCRCC patient
Figure 2: Differential gene expression between primary tumor (PT) and lymphatic metastasis (LM)
Figure 4: Plk5 mRNA perturbation during cell cycle and its protein expression support that Plk5 is a tumor suppressor.A

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