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CELLULAR TRANSPORT

(2)

The Fluid Mosaic Model

 The cell membrane is also called the

plasma membrane and is made of a

phospholipid bilayer.

(3)

 The phospholipids have a

hydrophillic (water attracting) head

 And two hydrophobic (water

repelling) tails.

(4)

Phospholipid

The phospholipid has a hydrophilic

(water loving) head and two

hydrophobic (water

fearing) tails.

(5)

Quiz

 1) Please draw a rough sketch of a cell membrane with 20

phospholipids, 2 integral proteins and 2 peripheral proteins.

 2) What does “HYDROPHOBIC”

mean?

 3) What does “HYDROPHILIC “ mean?

(6)

 Proteins called integral proteins go all the way through the bilayer

 While peripheral proteins are only on the outside or inside of the

membrane.

(7)

Quiz

 4) What is an integral protein?

 5) What is a peripheral protein?

(8)

 Integral proteins are also called channel proteins.

 Large molecules use integral proteins

to help move across cell membranes

(9)

 The plasma membrane helps a cell to maintain homeostasis, or a

relatively stable internal environment.

 It does this by being semi-permeable (it lets certain molecules inside of

the cell, while keeping others out).

(10)

Quiz

 6) The ability of a molecule to move across the membrane depends on what two things?

 7) How does the semi-permeability of the cell membrane help it

maintain homeostasis?

(11)

Diffusion

But what determines the

direction of the traffic across the membrane?

 Most solutes (or particles dissolved in

a solution) naturally want to spread

out from each other.

(12)

Diffusion

 So particles want to move from areas of high concentration to areas of low concentration.

 This is known as diffusion. Ex:

When you spray perfume, the perfume particles will spread out in the room.

If you drop food coloring into water, the

color will spread out.

(13)

Diffusion

 The particles will keep spreading out until the concentration is the same throughout the solution.

 Once the concentration is the same everywhere, the particles have

reached what we call equilibrium.

 Diffusion: The movement of

molecules from an area of high

concentration to an area of low

concentration.

(14)

Diffusion

 This process of diffusion is how some molecules move into and out of the cell.

 Since diffusion occurs naturally, the

cell does not need to use energy and

this is called PASSIVE transport.

(15)

Quiz

 8) Please define diffusion.

 9) Why is diffusion a passive

process?

(16)

Osmosis

 Osmosis is the diffusion of water

across a semi-permeable membrane.

 It is also driven by the concentration

of particles.

(17)

 Some particles cannot move across the membrane, so water moves

instead to even out the

concentration.

(18)

 A solution that has a high

concentration of particles is said to be HYPERtonic

 A solution that has low concentration

of particles is said to be HYPOtonic.

(19)

Solute

 We refer to the molecules in the as SOLUTE.

 Solute is measured in Moles (M).

 A solution that is 0.8M has more solute than a solution that is 0.4M.

 In this case the 0.4M solution is

Hypotonic. The 0.8M solution is

Hypertonic.

(20)

 Water will move from the hypotonic solution to the hypertonic solution, until the ratio of water to particles is the same on both sides.

 The solution is then said to be

ISOtonic (it has reached equilibrium).

(21)

Quiz

 10) Please define “OSMOSIS.”

 11) Of the 3 solutions, which is

Hypotonic and which is Hypertonic:

0.6M, 0.2M, and 1.0M

 12) If a cell that has 0.2M salt is put into a beaker of water that has 0.8 M salt. Which way will the water move:

into the cell, out of the cell, or into

and out of the cell the same amount.

(22)

Facilitated Diffusion

Non-lipid materials cannot diffuse across the membrane as easily as lipid molecules.

These substances must rely on special

proteins called channel or carrier proteins

that are embedded inside of the plasma

membrane.

(23)

Facilitated Diffusion

 Molecules will diffuse from one side of the cell membrane to the other side through the protein tunnels.

 Facilitated Diffusion is the diffusion of molecules through protein tunnels.

 Facilitated Diffusion

(24)

Facilitated Diffusion

 Since the substances are still travel from a high concentration to a low concentration,

 Facilitated diffusion does not require

the cell to use ATP (energy)

(25)

Quiz

 13) Please define “Facilitated Diffusion.”

 14) Why do you need facilitated

diffusion?

(26)

Active Transport

 As powerful as diffusion is, cells sometime have to use energy to move substances against the

concentration gradient (from low concentrations to high

concentrations).

 This is called active transport

(movement of molecules from a low concentration to a high

concentration with the use of

energy)

(27)

Active Transport- Transport proteins

 Embedded in the plasma membrane are special a) transport proteins, that b) use ATP (energy) to pump

molecules in or out of the cell.

(28)

Transport Proteins

 The proteins are similar to the carrier proteins that work in facilitated

diffusion, BUT they pump molecules from areas of low concentration to high concentration

 They require the use of energy (ATP) because they are going against the concentration gradient (low

concentration to a high concentration)

 Active Transport - Transport Protein

(29)

 Transport proteins are usually only

involved in the transfer of smaller

ions or molecules.

(30)

Quiz

 15) When does a cell need to use energy when transferring a

molecule?

 16) What two things are used in

active transport? Hint: one is ATP

(energy)

(31)

Quiz Answers

 1) Diagram will vary

 2) Water hating

 3) Water loving

 4) Integral proteins go all the way through the cell membrane.

 5) Peripheral proteins are on the

outside/inside of the cell membrane.

(32)

Quiz Answers

 6) the semi-permeability of plasma membrane and the size and charge of the particles that want to get

through.

 7) it lets certain molecules inside of the cell, while keeping others out

 8) Movement of molecules from an

area of high concentration to an area of low concentration.

 9) Diffusion requires no energy.

(33)

Quiz Answers

 10) Diffusion of water.

 11) o.2M Hypotonic, 1.0M Hypertonic

 12) The water will flow out of the cell.

 13) Diffusion of molecules through protein tunnels.

 14) Non-lipid materials cannot

diffuse across the membrane as

easily as lipid molecules.

(34)

Quiz Answers

 15) Have to use energy to move

substances against the concentration gradient (from low concentrations to high concentrations).

 16) ATP and Protein

References

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