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Human kinetochores are swivel joints that mediate microtubule attachments

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Figure

Figure 1. 3D dual colour kinetochore tracking assay demonstrates rigid intra-kinetochore structure
Figure 2. Nocodazole treatment marginally decreases 3D intra-kinetochore distance. (of a kinetochore pair demonstrating Gaussian-fitted spot centres
Figure 3. Outer kinetochore components are capable of ‘swivel’ about the inner kinetochore, which increases4291) cells compared to 3upon microtubule depolymerisation
Figure 4. Spatial and temporal control of kinetochore swivel. (A) Kinetochore pairs in centre (centre) and periphery(right) from a metaphase plate (left) showing Gaussian-fitted spot centres, #y-swivel, sister-sister axis and marker-marker axis

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