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<p>Deltonin Ameliorates Cerebral Ischemia/Reperfusion Injury in Correlation with Modulation of Autophagy and Inflammation</p>

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Academic year: 2020

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Figure

Figure 1 Deltonin’s chemical structure (A) and experiment protocol (B).
Figure 2 Deltonin improved neurological function and reduced cerebral infarction. For groups of sham, I/R, low-dose deltonin (25 mg/kg), medium-dose deltonin (50 mg/percentage
Figure 3 Deltonin reduced autophagy activities through PI3K/Akt/mTOR signaling. For groups of sham, I/R, high-dose deltonin (100 mg/kg) and high-dose+ LY294002: (GAPDH, LC3-II/GAPDH, LC3-I/GAPDH and Beclin-1/GAPDH.A)Neurological scores
Figure 4 TEM images showing the ultrastructural changes. The ultrastructural changes among sham, I/R, high-dose deltonin, and high-dose deltonin+LY294002 showed thatdeltonin reduced autophagy activities during cerebral I/R injury.
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