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Micropatterning of cells reveals chiral morphogenesis

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Academic year: 2020

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Figure

Figure 1. Two models for the initiation of left-right asymmetry in embryo development
Figure 2. Bias of single cell polarity. The red arrow shown is drawn from the center of the nucleus (blue) to the centrosome (green)
Figure 3. Left-right asymmetry on micropatterned surfaces. The cells are polarized at the boundary by positioning their centrosomes (green) and Golgi apparatuses (purple) closer to each boundary than nuclei (blue), while forming chiral alignment
Figure 4. Propagation of cell chirality with loss of geometric control. Cells preferentially attach to the fi bronectin (FN) domain immediately after plating onto alternating fi bronectin/polyethylene glycol (PEG) lanes, and they form a biased alignment wi

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