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Tau and Pet/Mri Imaging Biomarkers for Detecting and Diagnosing Early Dementia

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Figure

Figure 1. Higher temporal deposition especially in the hippocampus, the inferior temporal, and subcortical putamen/palladium (considered “off-target” binding) compared to mean cortical deposition and cerebellum (SUVR = 1) from group-averaged tau image.
Figure 2. a Brain regions clustered based on Braak staging from literature (Wang et al., 2016)
Figure 4. Significant correlations (corrected P < 0.01) between tau deposition and composite memory score in MCI patients
Figure 7. a: Significant voxel-wise negative correlation between tau and GM density were found in the entorhinal and hippocampal re-gions, medial and orbito-frontal as well as cerebellum; with few pos-itive correlations found in scattered brain regions inc

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