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Estimating the clinical cost of drug development for orphan versus non-orphan drugs

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Figure

Table 1 Number of trials and trial characteristics for all data
Fig. 1 Mean number of subjects in each trial phase for non-orphan and orphan groups. Missing = trial phase information not available
Table 2 Estimated clinical costs, expected costs and out-of-pocket clinical costs per approved drug
Fig. 3 Number of subjects by trial phase for NMEs only. NMEs = New Molecular Entities
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