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ANTIPROLIFERATIVE AND APOPTOGENIC EFFICACY OF ANTIDIABETIC DRUGS METFORMIN AND SITAGLIPTIN AGAINST MCF7 AND HEPG2 CANCER CELLS: A COMPARATIVE MOLECULAR STUDY

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Table 1: Determination of the IC50 of Metformin and Sitagliptin in MCF7 and HepG2 cells
Figure 1: After 24 h of treatment with both the drugs, the data explains the percentage of inhibition by the drugs which show that the drugs had affected the proliferative cancer cells much more than they inhibited the PBMNCs
Figure 3.2 demonstrates the effects of the anti-diabetic drugs upon HepG2 hepatocellular carcinoma cells
Figure 3: Fluorescent microscopic analysis after staining with Hoechst 33342 nuclear stain reveals the status of the nuclear fragmentation due to the treatment with sitagliptin and metformin
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