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Shape engineering vs organic modification of inorganic nanoparticles as a tool for enhancing cellular internalization

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Figure

Figure 2 The applied surface functionalization procedures for spherical and rod-shaped mesoporous silica nanoparticles.
Table 1 Characteristics of silica nanoparticle suspensions(0.5 mg/ml) in HEPES buffer (25 mM, pH 7.2)
Figure 4 Structural characteristics of the two different mesophases studied. (a) Powder X-ray diffraction (PXRD) pattern of a typical S-MSPstructure with hexagonally arranged pores (lattice spacing = 4.7 nm), (b) PXRD pattern of NR-MSP exhibiting hexagonal order with lattice spacingof 14.8 nm, (c) N2-sorption isotherm for S-MSP and (d) N2-sorption isotherm for NR-MSP, both of characteristic IUPAC type IV for mesoporousmaterials.
Figure 5 Cellular uptake of particles as studied by confocal fluorescence microscopy. Cellular uptake of uncoated rods (a and b) andspheres (c and d) vs PEI-functionalized S-MSPs (e and f) (spheres) in HeLa cells after 4 h incubation, resulting in differen
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