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Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis

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Figure

Fig. 1. Characterization of Ngn3-Venus fusion (NVF) reporter mouse line. (A) Immunohistochemical analysis indicates the same spatiotemporal expressionpattern of NVF and endogenous Ngn3 expression in heterozygous NVF (Ngn3+/Venus) pancreatic sections from E
Fig. 2. Identification of embryonic pancreatic epithelial populations at single cell resolution
Fig. 3. Lineage segregation of early pancreatic epithelial cells. (A) UMAP plot of all pancreatic lineages from four different early stages of embryonic pancreasdevelopment
Fig. 4. Gene expression profiles of endocrine progenitors-precursors (EPs). (A) UMAP plots showing the distribution of cells considered as Ngn3epithelial populations (E) and derived at different developmental stages (F)
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