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Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left right asymmetry

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Figure

Figure 1. Targeted disruption of the mouse hfh-4 gene. (a) Wild-type hfh-4 allele (top) is composed of two exons (solid boxes) with the DNA-binding domain (shaded boxes) split between exons I and II
Figure 2. Growth failure
Table I. Genotypes of Embryos from Heterozygous Matings
Figure 4. Absence of cilia in lung RNA. cDNA was prepared from e18.5 lung from hfh-4�/� mice

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