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Schoenheimer effect explained – feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

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Figure

Figure 1Targeted disruption of Insig1 and Insig2 genes in mice. (A) Schematic of Insig1 gene-targeting strategy
Figure 2Immunoblot (A) and lipid analysis (B) of livers from control and Insig-deficient mice
Table 2
Figure 3Lipid accumulation in livers of
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