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The positive feedback between snail and DAB2IP regulates EMT, invasion and metastasis in colorectal cancer

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Figure

Figure 1: DAB2IP KD promotes proliferation, invasion and EMT in CRC cells. A.HCT116 cell lines transfected with two specific shRNAs toward DAB2IP by real-time PCR
Figure 2: DAB2IP is sufficient to inhibit tumor growth and metastasis of CRC cells. A.tumor growth by MTT assay
Figure 3: Snail negatively regulates DAB2IP expression. A. Luciferase activity of DAB2IP promoter after transfection of Snail plasmid in HEK293A, SW480 and HCT116 cells
Figure 4: DAB2IP is negatively regulated by EZH2/HDAC/snail linear transcription complex
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