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Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice

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Figure

Figure 1AADC was selectively deleted in the renal proximal tubule in ptAadc–/– mice. (A) AADC was primarily expressed in kidney cortex in wild-type
Figure 2
Figure 4Renal cortical COX-2 and renin expression increased in pt
Figure 6Renal medullary COX-2 was inhibited in ptPGE**diet–induced (HS-induced) renal medullary COX-2 elevations were attenuated in ptCOX-2 immunoreactive protein in response to alterations of dietary salt intake represented as fold of expression of wild-t
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