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Somatic mutations in telomerase promoter counterbalance germline loss of function mutations

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Figure

Table 1. Blood leukocyte TERT promoter somatic mutations found in subjects with various heterozygous germline mutations in telomere-related genes
Figure 2. TERT promoter mutations are frequently found in cis with the WT TERT allele in blood leukocyte DNA haplotypes
Figure 3. TERT promoter mutation is associated with increased telomerase activity and a higher proliferative capacity

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