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Evidence against hypothalamic pituitary adrenal axis suppression in the antidiabetic action of leptin

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Academic year: 2020

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Figure

Figure 1. Hypercorticosteronemia is not required for hyperglycemia in STZ-DM. (A–D) Three-hour fasted plasma insulin (A) and leptin (B), and corticoster-one and ACTH levels (C) obtained mid-light cycle (13:00), and daily blood glucose levels (D) in the fed
Figure 2. Hyperglycemia in rats with STZ-DM is not reversed by either glucocorticoid receptor blockade or physiological leptin replacement
Figure 3. Suppression of hypercorticosteronemia is not required for leptin’s antidiabetic effects in STZ-DM

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