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WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors

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Academic year: 2020

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Figure

Figure 1WNT5A expression is increased in response to chronic inhibition of BRAFized to start of treatment (pre)
Figure 2WNT5A loss of function reduces melanoma cell number. (cells plated in soft agar, scored 1 week after siRNA transfection and embedding in soft agar
Figure 3WNT5A loss of function decreases the viability of both PLX-naive and PLX-resistant melanoma cells
Figure 4WNT5A overexpression enhances melanoma cell proliferation. (
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