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Modulation of glycogen synthase kinase-3β following TRAIL combinatorial treatment in cancer cells

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Figure 1: Attenuation of GSK3β pathway by combination treatment with TRAIL and TZD in prostate cancer cells.(A) LNCaP and (B) DU 145 cells were treated with a combination of TRAIL (100 ng/ml) and Troglitazone (50 μM) for different periods of time followed
Figure 2: Attenuation of GSK3β pathway in various cancer cells by TRAIL and TZD treatment
Figure 3: Comparison of the effects of TRAIL and TZD alone or in combination in antagonizing GSK3β pathway
Figure 4: TZD treatment attenuates GSK3β expression at a transcriptional level. (A) DU 145 cells were pretreated with 50 µg/ml Cycloheximide (CHX) for 48 hrs and then with DMSO or TRAIL, TZD alone or in combination for an additional 24 hrs
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