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Activation of SGK1 in endometrial epithelial cells in response to PI3K/AKT inhibition impairs embryo implantation

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Figure

Fig 1. Modulation of SGK1 activity by different PI3K/AKT inhibitors. Ishikawa cells, cultured at 80% con-fluency, were treated with various PI3K/AKT inhi-bitors (at 20 µM, except for inhibitor IV, which was used at 1 µM concentration) for a total of 2 hour
Fig 2. Modulation of SGK1 activity by inhibitor III and V. (A) Ishikawa cells, cultured at 80% confluency, were treated with various PI3K/AKT inhibitor III or V for a total of 2 hours
Fig 3. Modulation of SGK1 activity by AKT-inhibitor peptide. Ishikawa cells, cultured at 80% confluency, were treated with an AKT inhibitor peptide or a control peptide for a total of 2 hours
Fig. 5. Effect of AKT inhibitor III on amiloride-sensitive Na+ currents in Ishikawa cells
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