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Original Article A DNA vaccine encoding a chimeric allergen derived from major group 1 allergens of dust mite can be used for specific immunotherapy

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Academic year: 2020

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Figure

Figure 1. Representation of the reporter and targeting vectors. PCMV (black arrow): Human cytomegalovirus imme-diate-early promoter; GFP (green box): enhanced green fluorescent protein; BGH pA (black box): The bovine growth hormone polyadenylation sequence
Figure 2. Immunization schematic of the initiation of allergen-induced allergic airway inflammation in the mouse model and treatment with the DNA vaccine construct.
Figure 3. Detection of R8 gene expression in HEK 293T cells by fluoresent microscopy, 46 hours after treatment with the DNA-liposome complex (×200).
Figure 5. Pathological examinations of mouse lungs by H&E staining (×400). A: PBS group; B: asthma group; C: pcDNA3.1 group; D: pcDNA3.1-GFP group; E: pcDNA3.1-GFP-ProDer f1 group; F: pcDNA3.1-GFP-R8 group
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