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Long term exposure to a high fat diet results in the development of glucose intolerance and insulin resistance in interleukin 1 receptor I deficient mice

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Figure

Fig. 1. Lack of IL-1 receptor I (IL-1RI) results in development of glucose intolerance and insulin resistance after 6 mo high-fat diet (HFD)
Table 1. Plasma metabolic profile
Fig. 2. Adipose morphology of IL-1RI�[*(tissue was monitored by flow cytometry and correlated to the weight of individual mice (for each individual mouse was calculated and is presented (/� mice switched from hyperplasia after 3 mo HFD to hypertrophy after
Fig. 3. IL-1RI�/� mice develop mature-onset obesity on a low-fat diet (LFD) but have preserved glucose homeostasis and negligible adipose tissue inflammation.A: weight of male WT and IL-1RI�/� mice (8–10 wk old) after 6 mo on HFD or LFD (n � 9–34)
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