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The Positive Outlook Study: A Randomised Controlled Trial Evaluating Online Self- Management for HIV Positive Gay Men

Tanya Millard, Paul A Agius2, 3, Karalyn McDonald1, 4, 5, Sean Slavin6, Sonya Girdler7 & Julian H Elliott1,2,8.

1Department of Infectious Diseases, Monash University, Melbourne, Australia; 2Centre for Population Health, Burnet Institute, Melbourne, Australia; 3 Judith Lumley Centre, La Trobe University, Melbourne, Australia; 4Jean Hailes Research Unit, Monash University; 5Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Australia; 6Centre for Social Research in Health, University of New South Wales, Sydney, Australia; 7School of Occupational Therapy and Social Work, Curtin University, Perth, Australia; 8Infectious Diseases Unit, Alfred Hospital, Melbourne, Australia.

Background

 HIV now a chronic condition

 Psychosocial issues prominent

 Self-management

Client central in managing physical, social, emotional aspects

Widely used in chronic disease management

Effective at improving health outcomes

Effectiveness for PWHIV has not been well established

 Barriers to existing programs for PWHIV: time; location;

transport; stigma; desire for anonymity; lack of association with community organisations

Background

 Online intervention delivery - improved access and reduced associated costs

 Beneficial for populations who are diverse and difficult to engage in existing services

 Increased number of HIV-specific websites; online delivery increasingly employed in HIV programming

 Lack of empirical evidence regarding efficacy

The Positive Outlook Program

 Based on self-efficacy theory; utilised a self-management approach

 The intervention encouraged participants to take responsibility for the self-management of their condition including managing physical, social and emotional aspects of health and making behavioural changes

 Full intervention description in protocol paper*

*Millard T, Elliott J, Slavin S, McDonald K, Rowell S, Girdler S: The positive outlook study- a randomised controlled trial evaluating the effectiveness of an online self-management program targeting psychosocial issues for men living with HIV: a study protocol. BMC Public Health 2014, 14:106.

The Positive Outlook Program

Enhance participants’ (MSM) skills, confidence and abilities to manage the psychosocial aspects of HIV in their daily lives.

 Closed group

 7 week program, ~90 minutes per week

 Information modules (10-15 web pages); goal setting and action planning activities; discussion boards; weekly live chat

 Peer-facilitated

 Participants used pseudonyms

• Orientation

• Maintaining a healthy lifestyle- setting health related goals etc Week 1

• HIV and You: the emotional impact of HIV; and maintaining social connectedness

Week 2

• Talking about HIV: Disclosure to friends, family and acquaintances.

Week 3

• HIV You and Others (Part 1): HIV and intimate relationships; safe sex basics:

and sexually transmitted infections.

Week 4

• HIV You and Others (Part 2): Disclosure to intimate partners; seeking new relationships; and dealing with rejection.

Week 5

• HIV You and Others (Part 3): Managing HIV within intimate relationships and negotiating risk reduction strategies.

Week 6

• Wrap up: Reflect and review Week 7

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Methods

 Randomised Controlled Trial

 Research Question: What is the effectiveness of the Positive Outlook program on improving general health and HIV-specific outcomes compared with usual care only?

Methods

Inclusion Criteria

HIV positive men over 18 years living in Australia

Self-identified as gay or MSM

Ability to read and write in English

Self-reported access to a computer and the Internet for >90 minutes per week for seven weeks

Adequate computer skills

National recruitment

Outcome Measures

 Three time-points: (1) after randomisation, (2) at conclusion of intervention and (3) at 12 week follow-up.

Primary Outcomes:

1. HIV-related quality of life (PROQOL-HIV) 2. Outcomes of health education (heiQ) 3. Positive Outlook Self-Efficacy Scale (POSE)

Secondary Outcomes:

Quality of life (SF12)

Duke Social Support Index (DSSI)

Depression, Anxiety and Stress Scale (DASS21)

Mental Adjustment to HIV Scale (MAH)

General Self Efficacy Scale (GSE)

Flow of Participants

Registered interest (n= 227)

Completed baseline questionnaire & randomized (n= 132) Registered interest (n= 227)

Completed baseline questionnaire & randomized (n= 132)

Statistical Analysis

 Contingency table analyses comparing baseline characteristics

 Maximum likelihood marginal-linear modelling on repeated measures data

Results

Participant characteristics

 Median age 43

 72% born in Australia

 67% single; 72% tertiary qualification; 40% live alone

 60% full-time employment; 15% part-time; 25%

unemployed

 Median length of diagnosis 6 years

 80% on ART

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3 PROQOL-HIV

† robust standard errors specified in modelling

^ p-values are Bonferonni adjusted

PHS – Physical health and symptoms; BC – Body change; SR – Social relationships; IR – Intimate relationships; ST – Stigma; ED – Emotional distress; HC – Health concerns; TI – Treatment impact;

HeiQ

† robust standard errors specified in modelling

^ p-values are Bonferonni adjusted

HDA – Health directed activity; PAE – Positive and active engagement in life; ED – Emotional distress; SM – Self monitoring and insight; CAA – Constructive attitudes and approaches; STA – Skill and technique acquisition; SIS – Social integration and support; HSN – Health service navigation.

Positive Outlook Self-Efficacy Scale (POSE)

† robust standard errors specified in modelling

^ p-values are Bonferonni adjusted

Discussion/ Conclusions

 Significant improvements in quality of life, self-management skills and domain specific self-efficacy for gay men with HIV

 Consistent improvements in emotional distress and social relationships/participation

 Pattern of diminishing effect

Participant engagement

Duration

 Further research needed to explore long-term effectiveness

Discussion/ Conclusions

 Limitations: sample size; high loss to follow-up; short follow-up

 Innovative programs are required to address pervasive issues

 Online delivery: feasible, effective, well-accepted and anonymous

Acknowledgements

Sexual Health and Blood Borne Virus Program; Australian Postgraduate Award

Watson Browne Bequest; NAPWHA

NAPWHA; VAC; Living Positive Victoria; ACON; WAAC

Recruiting partners

Participants

Facilitators

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Questions?

[email protected]

Thank you!

References

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