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Biomaterial based endochondral bone regeneration: A shift from traditional tissue engineering paradigms to developmentally inspired strategies

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Figure

Fig. 1. Schematic illustrating combinations of bio-materials, cells, and signaling factors for the tissueengineering of hypertrophic cartilaginous grafts invitro
Fig. 2. Assessment of repair of rat cranial bonecalcium phosphate scaffold showing good levelsof healing 4 weeks after implantation in compar-ison to (b)which showed limited levels of repair
Fig. 3. Schematic illustration of hypothesized biomaterial-based endochondral bone regeneration in vivo
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