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(1)

Circulatory System

Circulation

Blood Vessels

Blood

Heart

(2)

Overview of Circulation

Pulmonary circulation:

blood flow between the heart and lungs

Systemic circulation:

blood flow from heart to rest of the body

Cardiac circulation:

(3)

Pulmonary Circulation

(4)

Systemic Circulation

(5)

Cardiac Circulation

(6)

(capillaries) Lung

Vein pulmonary circulation Artery

HEART

Vein systemic circulation Artery

Body

(7)

Blood Vessel Function

Vessel Function Examples

Artery Transports blood AWAY from the heart

Aorta

Pulmonary artery

Vein Transports blood TOWARDS the heart

Vena cava

Pulmonary vein

Capillary Material exchange

between blood and body

(8)

Pathway of Blood Flow

http://www.tracleer.com/Content/Images/heart-lung-circulation.jpg

Artery

Artery Vein

(9)

Pathway of Blood Flow

http://media.web.britannica.com/eb-media/06/92806-034-95B4D32F.jpg

(10)

Blood Vessels

(11)

Blood Vessel Structure

Vessel Wall

Thickness Diagram Pressure

Artery Thick High

Vein Thin Low

(12)

Artery Structure

Thick walls: withstand high pressure from heart Elastic walls: expand & contract to help pump

(13)

Vein Structure

Thinner walls

Larger circumference Low blood pressure

Need structure to help move blood against

(14)

Vein: One-way valves

Valves open when

muscles contract, allowing blood to move forward

Valves close when

muscles relax so that blood cannot flow backwards

(15)

Vein: One-way valves

(16)

Varicose Veins: Deformed Valves

(17)

Capillary Structure

Small diameter in capillaries are

only wide enough for red blood cells to travel in a single file

Red blood cells pull each other

along like a chain

(18)

Capillary Structure

Walls made up of one layer of epithelial cells Cells are smooth to reduce friction

(19)

Capillary Function

Rapid diffusion of

materials into and out of blood

http://faculty.stcc.edu/AandP/AP/imagesAP2/bloodvessels/endothelia.jpg Molecules Into capillaries Out of capillaries

Oxygen Lungs Body cells

(20)

Diffusion in Capillaries of Body

(21)

Diffusion in Capillaries of Lung

(22)

Movement of Gases

http://www.tracleer.com/Content/Images/heart-lung-circulation.jpg

Artery

Artery Vein

Vein

Oxygen Carbon dioxide

(23)

Blood Flow in Blood Vessels

Vessel Structure that

aids blood flow Explanation

Artery

Vein

(24)

Blood Flow in Blood Vessels

Vessel Structure that

aids blood flow Explanation

Artery Elastic walls Walls expand & contract helping to pump blood

Vein One-way valves Valves act as doors preventing backward blood flow

Capillary Small

circumference

Blood cells travel in single file

(25)

Blood Components

(26)

Blood Components

Type Structure Function %

makeup Red blood cells No nucleus Disk-shaped, flexible Contains hemoglobin Transports oxygen 45 White blood cells

Have a nucleus Short life span

Fights

infections <1

Platelets Made of cell fragments Blood

clotting <1

Plasma Protein-rich liquid Contains electrolytes

Carries

(27)
(28)

Animations

Circulatory System Animation

http://www.youtube.com/watch?v=PgI80Ue-AMo

3D model of Working Heart

https://www.youtube.com/watch?v=NF68qhyfcoM&feature=related

3D cardiac circulation (silent)

https://www.youtube.com/watch?v=06iQlVMSB34&feature=fvwrel

Cardiac Circulation Summary

https://www.youtube.com/watch?v=DAXa4eR1s0M&feature=related

0:18 – 2:05

Circulatory song

(29)
(30)

Cardiac

Circulation

4 chambers 4 valves

2 arteries 2 veins

Deoxygenated

blood

Oxygenated

blood

(31)

Superior vena cava

(32)

Superior vena cava

Inferior vena cava

Right atrium

(33)

Superior vena cava

Inferior vena cava Right atrium

Tricuspid valve

(34)

Superior vena cava

Inferior vena cava Right atrium

Tricuspid valve Right ventricle

(35)

Pulmonary artery Pulmonary artery Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve

to right lung

(36)
(37)

Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary artery

from right lung

from right lung

from left lung

(38)

from right lung Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery

from right lung

Pulmonary artery

from left lung

from left lung

(39)

Left atrium Pulmonary artery Pulmonary vein Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary vein

(40)

Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary vein Pulmonary artery Left atrium Pulmonary vein

Mitral valve or bicuspid valve

(41)

Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary vein Aortic valve Pulmonary artery Left atrium Pulmonary vein

Mitral valve or bicuspid valve

(42)

Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary vein Pulmonary artery Left atrium Pulmonary vein

(43)

Pulmonary artery

Left atrium

Pulmonary vein

(44)
(45)

Circulation

right atrium right ventricle pulmonary artery

arterioles

capillaries of lungs

venules pulmonary vein left atrium left ventricle aorta arterioles

capillaries of body

venules vena cava

Cardiac circulation Pulmonary circulation

(46)

(capillaries) Lung

Vein pulmonary circulation Artery

HEART

Vena Cava systemic circulation Aorta

Body

(capillaries)

The Pathway of Blood Flow

(47)

Left atrium

Left ventricle

Right atrium

Right ventricle

(48)

Left atrium

Left ventricle

Right atrium

Right ventricle

Septum

(49)

Cardiovascular Diseases

Congenital Heart Defect Arrhythmias

Heart murmurs

Atherosclerosis

Disorders related to atherosclerosis:

Coronary Artery Disease

Hypertension

Heart attack

(50)

Congenital Heart Defect

Defect of the

structure of the heart and vessels, present at birth

Example: Septal

defect

a hole in the septum

allows oxygenated

(51)

Arrhythmia

Heart beats irregularly

Arises from problems with the electrical

(52)

Electrocardiograph (ECG)

(53)

Arrhythmia

Treatment may

include implanting an artificial

(54)
(55)

Valves

Pulmonary valve (semilunar)

Aortic valve (semilunar)

Mitral / Bicuspid valve (AV)

(56)

Tricuspid Valve Mitral Valve

(57)

Heart Murmurs

heart makes extra

(58)

Cardiovascular Diseases

Congenital Heart Defect

Arrhythmias

Heart murmurs

Atherosclerosis

Disorders related to atherosclerosis:

Coronary Artery Disease

Hypertension

Heart attack

(59)

Atherosclerosis

Accumulation of plaque on the artery wall

Plaque formation begins at the site of tear in

artery wall

Fat and cholesterol can accumulate which

(60)

Blockage

Partial plaque blockage

can lead to:

Coronary artery disease

Hypertension

Complete plaque blockage

can lead to:

Heart attack

(61)

Coronary Artery Disease

Plaque in the coronary arteries

Coronary artery: supplies blood to heart

muscle cells

Why is it important to

(62)

Effects of Plaque

hardened arteries:

limits elasticity of artery wall

narrowed arteries:

reduces blood and oxygen flow

(63)

Prolonged high blood

pressure

Heart is constantly

pumping harder

Overuse leads to

thickening of heart

muscles making them less flexible and more inefficient at pumping

(64)

Plaque blockage

Rupture of plaque resulting in a blood clot

Platelets and other blood clotting factor

Cause of Complete Blockage

(65)

Heart Attack

Blocked blood flow in coronary artery

Lack of oxygen flow to heart muscle cells Death of heart muscle cells

Heart may stop pumping

(66)

Stroke

“Brain attack” Lack of oxygen

flow to brain

Blocked or burst

arteries that

(67)

Atherosclerosis Treatments

Coronary bypass Angioplasty

Stent

Videos

Angioplasty & Stenting (1:07)

http://www.youtube.com/watch?v=S9AqBd4REx k&feature=related

Angioplasty & Stenting Animation - no narrative

(4:16)

(68)
(69)
(70)
(71)

Atherosclerosis Treatments:

Stent

(72)

Atherosclerosis Treatments:

Stent

http://www.youtube.com/watch?v=PgI80Ue-AMo https://www.youtube.com/watch?v=NF68qhyfcoM&feature=related https://www.youtube.com/watch?v=06iQlVMSB34&feature=fvwrel https://www.youtube.com/watch?v=DAXa4eR1s0M&feature=related http://www.youtube.com/watch?v=q0s-1MC1hcE&feature=related http://www.youtube.com/watch?v=M0NF2ODfd9E http://www.youtube.com/watch?v=YcNYxegDXa8&feature=related http://www.youtube.com/watch?v=S9AqBd4RExk&feature=related https://www.youtube.com/watch?v=p3z9FLYijrQ

References

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