Circulatory System
Circulation
Blood Vessels
Blood
Heart
Overview of Circulation
Pulmonary circulation:
blood flow between the heart and lungs
Systemic circulation:
blood flow from heart to rest of the body
Cardiac circulation:
Pulmonary Circulation
Systemic Circulation
Cardiac Circulation
(capillaries) Lung
Vein pulmonary circulation Artery
HEART
Vein systemic circulation Artery
Body
Blood Vessel Function
Vessel Function Examples
Artery Transports blood AWAY from the heart
Aorta
Pulmonary artery
Vein Transports blood TOWARDS the heart
Vena cava
Pulmonary vein
Capillary Material exchange
between blood and body
Pathway of Blood Flow
http://www.tracleer.com/Content/Images/heart-lung-circulation.jpg
Artery
Artery Vein
Pathway of Blood Flow
http://media.web.britannica.com/eb-media/06/92806-034-95B4D32F.jpg
Blood Vessels
Blood Vessel Structure
Vessel Wall
Thickness Diagram Pressure
Artery Thick High
Vein Thin Low
Artery Structure
Thick walls: withstand high pressure from heart Elastic walls: expand & contract to help pump
Vein Structure
Thinner walls
Larger circumference Low blood pressure
Need structure to help move blood against
Vein: One-way valves
Valves open when
muscles contract, allowing blood to move forward
Valves close when
muscles relax so that blood cannot flow backwards
Vein: One-way valves
Varicose Veins: Deformed Valves
Capillary Structure
Small diameter in capillaries are
only wide enough for red blood cells to travel in a single file
Red blood cells pull each other
along like a chain
Capillary Structure
Walls made up of one layer of epithelial cells Cells are smooth to reduce friction
Capillary Function
Rapid diffusion of
materials into and out of blood
http://faculty.stcc.edu/AandP/AP/imagesAP2/bloodvessels/endothelia.jpg Molecules Into capillaries Out of capillaries
Oxygen Lungs Body cells
Diffusion in Capillaries of Body
Diffusion in Capillaries of Lung
Movement of Gases
http://www.tracleer.com/Content/Images/heart-lung-circulation.jpg
Artery
Artery Vein
Vein
Oxygen Carbon dioxide
Blood Flow in Blood Vessels
Vessel Structure that
aids blood flow Explanation
Artery
Vein
Blood Flow in Blood Vessels
Vessel Structure that
aids blood flow Explanation
Artery Elastic walls Walls expand & contract helping to pump blood
Vein One-way valves Valves act as doors preventing backward blood flow
Capillary Small
circumference
Blood cells travel in single file
Blood Components
Blood Components
Type Structure Function %
makeup Red blood cells No nucleus Disk-shaped, flexible Contains hemoglobin Transports oxygen 45 White blood cells
Have a nucleus Short life span
Fights
infections <1
Platelets Made of cell fragments Blood
clotting <1
Plasma Protein-rich liquid Contains electrolytes
Carries
Animations
Circulatory System Animation
http://www.youtube.com/watch?v=PgI80Ue-AMo
3D model of Working Heart
https://www.youtube.com/watch?v=NF68qhyfcoM&feature=related
3D cardiac circulation (silent)
https://www.youtube.com/watch?v=06iQlVMSB34&feature=fvwrel
Cardiac Circulation Summary
https://www.youtube.com/watch?v=DAXa4eR1s0M&feature=related
0:18 – 2:05
Circulatory song
Cardiac
Circulation
4 chambers 4 valves
2 arteries 2 veins
Deoxygenated
blood
Oxygenated
blood
Superior vena cava
Superior vena cava
Inferior vena cava
Right atrium
Superior vena cava
Inferior vena cava Right atrium
Tricuspid valve
Superior vena cava
Inferior vena cava Right atrium
Tricuspid valve Right ventricle
Pulmonary artery Pulmonary artery Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve
to right lung
Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary artery
from right lung
from right lung
from left lung
from right lung Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery
from right lung
Pulmonary artery
from left lung
from left lung
Left atrium Pulmonary artery Pulmonary vein Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary vein
Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary vein Pulmonary artery Left atrium Pulmonary vein
Mitral valve or bicuspid valve
Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary vein Aortic valve Pulmonary artery Left atrium Pulmonary vein
Mitral valve or bicuspid valve
Superior vena cava Inferior vena cava Right atrium Tricuspid valve Right ventricle Pulmonary valve Pulmonary artery Pulmonary vein Pulmonary artery Left atrium Pulmonary vein
Pulmonary artery
Left atrium
Pulmonary vein
Circulation
right atrium right ventricle pulmonary artery
arterioles
capillaries of lungs
venules pulmonary vein left atrium left ventricle aorta arterioles
capillaries of body
venules vena cava
Cardiac circulation Pulmonary circulation
(capillaries) Lung
Vein pulmonary circulation Artery
HEART
Vena Cava systemic circulation Aorta
Body
(capillaries)
The Pathway of Blood Flow
Left atrium
Left ventricle
Right atrium
Right ventricle
Left atrium
Left ventricle
Right atrium
Right ventricle
Septum
Cardiovascular Diseases
Congenital Heart Defect Arrhythmias
Heart murmurs
Atherosclerosis
Disorders related to atherosclerosis:
Coronary Artery Disease
Hypertension
Heart attack
Congenital Heart Defect
Defect of the
structure of the heart and vessels, present at birth
Example: Septal
defect
a hole in the septum
allows oxygenated
Arrhythmia
Heart beats irregularly
Arises from problems with the electrical
Electrocardiograph (ECG)
Arrhythmia
Treatment may
include implanting an artificial
Valves
Pulmonary valve (semilunar)
Aortic valve (semilunar)
Mitral / Bicuspid valve (AV)
Tricuspid Valve Mitral Valve
Heart Murmurs
heart makes extra
Cardiovascular Diseases
Congenital Heart Defect
Arrhythmias
Heart murmurs
Atherosclerosis
Disorders related to atherosclerosis:
Coronary Artery Disease
Hypertension
Heart attack
Atherosclerosis
Accumulation of plaque on the artery wall
Plaque formation begins at the site of tear in
artery wall
Fat and cholesterol can accumulate which
Blockage
Partial plaque blockage
can lead to:
Coronary artery disease
Hypertension
Complete plaque blockage
can lead to:
Heart attack
Coronary Artery Disease
Plaque in the coronary arteries
Coronary artery: supplies blood to heart
muscle cells
Why is it important to
Effects of Plaque
hardened arteries:
limits elasticity of artery wall
narrowed arteries:
reduces blood and oxygen flow
Prolonged high blood
pressure
Heart is constantly
pumping harder
Overuse leads to
thickening of heart
muscles making them less flexible and more inefficient at pumping
Plaque blockage
Rupture of plaque resulting in a blood clot
Platelets and other blood clotting factor
Cause of Complete Blockage
Heart Attack
Blocked blood flow in coronary artery
Lack of oxygen flow to heart muscle cells Death of heart muscle cells
Heart may stop pumping
Stroke
“Brain attack” Lack of oxygen
flow to brain
Blocked or burst
arteries that
Atherosclerosis Treatments
Coronary bypass Angioplasty
Stent
Videos
Angioplasty & Stenting (1:07)
http://www.youtube.com/watch?v=S9AqBd4REx k&feature=related
Angioplasty & Stenting Animation - no narrative
(4:16)
Atherosclerosis Treatments:
Stent
Atherosclerosis Treatments:
Stent