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<p>The unique invasiveness of glioblastoma and possible drug targets on extracellular matrix</p>

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Figure

Figure 1 A summary of proteases secretion by GBM cells and their actions upon activation.Notes: Several positive feedback loops of activation exist
Figure 2 A Matrigel assay: an invasion assay which allows the experimenters to assess the invasive potential of cells through the Matrigel-filled pores in a membrane separating the two compartments; this resembles invasion through the eCM.Abbreviation: eCM, extracellular matrix.
Figure 3 Diagram showing the hydrodynamic model of invasion.channels. water then follows out of the cell through aquaporins down its osmotic gradient
Table 1 A summary of the current ongoing Phase iii and Phase iv trials

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