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Intracellular Acidification in Brain Tumors Induced by Topiramate : In-Vivo Detection Using Chemical Exchange Saturation Transfer Magnetic Resonance Imaging

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Figure

Figure 1.1 Glioblastoma Tumor-An example T2-weighted MRI of a large glioblastoma tumor is shown in the parietal region of the human brain
Figure 1.3 pH control mechanisms of cancer cells. In tumors, the rate of aerobic glycolysis is elevated due to increased cell proliferation
Figure 1.4 The roll of CA and AQP1 in tumor pH regulation. In tumor cells aerobic glycolysis is elevated causing increased production of lactate and H+
Figure 1.5 Effect of pHe/pHi on distribution of drugs. The font size indicates the relative concentration in that compartment
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