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Investigating isoquinoline derivatives for inhibition of inhibitor of apoptosis proteins for ovarian cancer treatment

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Figure

Figure 1B demonstrated that B01002 and C26001, both at
Figure 1 B01002 and c26001 inhibited sKOV3 cell proliferation and promoted apoptosis in vitro
Figure 2 B01002 and c26001 inhibited tumor growth on sKOV3 xenograft mouse model. (A) Tumor growth curves of different treatment groups of PBs, DDP, B01002, and c26001
Figure 3 B01002 and c26001 inhibited tumor proliferation in vivo. (A) left, representative Ki-67 staining images of tumors resected from tumor-bearing mice treated with B01002, C26001, DDP, or PBS, magnification ×100; Right, the ratio of positive Ki-67 nuc
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