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Genetic clustering and polymorphism of the merozoite surface protein 3 of Plasmodium knowlesi clinical isolates from Peninsular Malaysia

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Academic year: 2020

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Figure

Fig. 1 Domain structures in pkmsp3. Organisation of the pkmsp3 gene showing the positions of coiled-coil region identified as Domain A (yellow),the C-terminal region as Domain B (blue) and the signal peptide (green)
Fig. 2 Nucleotide polymorphism in the pkmsp3. Sliding window plotof the nucleotide diversity (π) along the pkmsp3, generated with awindow length of 100 bp and step size of 25 bp
Table 2 Haplotypes of pkmsp3 detected in human bloodsamples. Each blood sample was assigned a reference code(alphabetical or numerical)
Fig. 4 Phylogenetic tree of pkmsp3 haplotypes. The neighbour joining method was used to construct the tree, which contains 42 haplotypes.Numbers at the nodes indicate percentage support of 1000 bootstrap replicates
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