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Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis

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Figure

Table 1 Details of the three SOD1-related ALS cases andseven neurologically normal controls
Figure 1 Interacting pathways of cell survival present in the mtSOD1 motor neurons. (levels of diacylglycerol are available for protein kinase C epsilon activation
Figure 3 Western blotting of primary motor neuronal cultures transfected with constructs over expressing wild-type (WT) or C124Smutant PTEN or transduced with small interfering RNA against PTEN (siPTEN) and scrambled small interfering RNA against PTEN(SsiP
Figure 4 Results of transduction of primary motor neuronal cultures originating from G93A SOD1 mice and litter mates with smallmeansand increase in phosphorylation of AKT and Bcl2-antagonist of death (interfering RNA (siRNA) against PTEN and scrambled smal

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