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Highly Pathogenic H5N1 Avian Influenza Virus Induces Extracellular Ca2+ Influx, Leading to Apoptosis in Avian Cells

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Figure

FIG. 1. Cytotoxicity of DEF infected with AIVs. DEF were in-fected with each of the indicated AIVs at an MOI of 3 for 1 h
FIG. 2. Quantitative analysis of viral transcripts and progeny viri-ons. (A) The kinetics of viral mRNA expression levels were quantified
FIG. 4. Caspase activity in DEF infected with AIVs. (A) The ac-tivities of caspases 3/7 (left panel), 8 (middle panel), and 9 (right
FIG. 6. The levels of [Ca2AIVs. At 24, 36, and 48 h p.i., DEF mock infected or infected withCw/Kyoto or Dk/HK were stained with 5three panels) or 10min at 37°C, as an indicator of [Ca�]i and [Ca2�]m in DEF infected with �M Fluo-4 AM (green; top �M Rhod-2 A
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