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ATR and ATRIP Are Recruited to Herpes Simplex Virus Type 1 Replication Compartments Even though ATR Signaling Is Disabled

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Academic year: 2019

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Figure

FIG. 1. ATRIP colocalizes with ICP8 in HSV-1 replication compartments. Vero cells were infected with HSV-1 at an MOI of 10 for 6 h.(A) Cells were fixed and stained with the indicated ATRIP antibody, ICP8 to indicate replication compartments, and rat Hsc70 to indicate VICE
FIG. 2. ATRIP antibodies recognize proteins of different sizes byWestern blot analysis
FIG. 4. ATR colocalizes with ICP8 in HSV-1 replication compartments. Vero cells were transfected with wild-type Flag-ATR (wt) orkinase-dead Flag-ATR (kd) and infected with HSV-1 at an MOI of 10 for 6 h
FIG. 6. ATRIP and RPA but not phospho-RPA are in stage IImicrofoci. Vero cells were infected with HSV-1 at an MOI of 2 for 6 h.
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