• No results found

Generation of GHR modified pigs as Laron syndrome models via a dual sgRNAs/Cas9 system and somatic cell nuclear transfer

N/A
N/A
Protected

Academic year: 2020

Share "Generation of GHR modified pigs as Laron syndrome models via a dual sgRNAs/Cas9 system and somatic cell nuclear transfer"

Copied!
14
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Fig. 1 Establishment of GHR‑modified single‑cell colonies. a Schematic diagram of DNA deletion mediated by the dual‑sgRNAs/Cas9 system
Fig. 2 Highly efficient DNA deletion mediated by dual‑sgRNAs/Cas9. a Detected modified GHR sequences of 40 alleles in 20 single‑cell colonies
Table 1 Development of reconstructed GHRKO cloned embryos after transfer to recipient gilts
Fig. 3 Detection of dual‑sgRNAs/Cas9‑mediated GHR modification in piglets. a, b Picture of GHRKO pigs showing their small stature and normal fertility
+3

References

Related documents

In the present study, the systemic toxicities of both naked LDH (nak-LDH) nanoparticles and lipid membrane-coated LDH (lip-LDH) nanoparticles were examined because of the

Consequently, the Minister fiir Umwelt, Naturschutz und Reaktorsicherheit (Minister for the Environment, Conservation of Nature and Nuclear Safety) has recently

Methods: 60 elderly patients with laparoscopic abdominal surgery were selected for study and randomly divided into two groups ( n =30), group A received ventilation in

text), see DiFranco v. The Act, however, does not limit the victim's rights under a private insurance contract. Where a victim is entitled to compensation under

While embelin showed antibacterial activity against B.subtilis (Gram + ve) and antifungal activity against C.albicans, the activity was completely knocked off in all compounds

The aim of this research is to study the efficiency of removing copper ions and Zinc ions from Copper Chloride and Zinc Chloride, using naturally based adsorbents like

Analysis of HTS data on body composition measured by DEXA on 3651 KO lines fed chow diet from weaning showed that G2e3 KO mice, but not Prkd1 KO mice, had increased % body fat

1) The impact of internal customer satisfaction on the performance of maintenance of equipments in industries. 2) The dimensions of service quality which have caused internal