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Inhibition of apoptosis in the primary enamel knot does not affect specific tooth crown morphogenesis in the mouse

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Academic year: 2020

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Figure

Fig. 1. Histological sec-tions of E-13.5 firstshow apoptotic bodies(arrows) in the area ofvitro in control me-void of apoptotic bod-the enamel knot (EK)
Figure 5B, C, D show the distribution pattern of BrdU negativecells in a molar after 3 days of post-culture
Fig. 4. Histological sections of E-13.5 first lower molars (A-E) and of E-12 lower incisorsDuring mouse tooth development, bud-capdeoxyuridine negative (BrdU-) and 5-bromo-2'-deoxyuridine positive (BrdU+) areas are ob-presence of the caspase inhibitor, the
Fig. 5. Computer assisted 3-D reconstruction of an E-13.5first lower molar cultured for 6 days in control medium (A)and E-13.5 first lower molars cultured in vitro for 2 days inthe presence of 200 µM of Z-VAD-fmk and post-cultured incontrol medium for 3 (B
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