Collagen I, fibronectin, IL-1, IL-6 expression in high glucose group, Ad-EGFP group, Ad-PRR group and Ad-PRR+PD98059 group in vitro in cardiac fibroblasts.. A: Collagen I mRNA
The results showed that NE induced CFs proliferation and differentiation, increased α-SMA protein expression, increased collagen I, collagen III and fibronectin production, promoted ECM
Ang II treatment of rat mesangial cells in culture increased TGF-beta and matrix components biglycan, fibronectin, and collagen type I at both the mRNA and protein levels in a time- and
Interleukin 4 also known as "B cell stimulatory factor-1", a cytokine product of T lymphocytes and mast cells, stimulates synthesis of the extracellular matrix proteins, types I and III
Analysis of mRNA for both the a 1 chains of collagen type I and III, which represent the most abundant forms of collagen in the extracellular matrix of cardiac tissue, also showed major
To determine if fibrillin production was abnormal in cells from individuals with the Marfan syndrome, we studied the synthesis, secretion, and extracellular matrix incorporation of
In order to identify the cell-specific changes that occur in extracellular matrix gene expression during hepatic fibrosis in vivo, mRNA levels for collagen types I, III, and IV, and
Dermal fibroblasts cultured from patients with scleroderma produce more types I and III collagen than fibroblasts from normal subjects 36-38; this enhanced collagen synthesis is
In addition, the effects of TGF-,B on glomerular cell proliferation and on the production of collagen and fibronectin synthesized by mesangial and epithelial cells are described..
Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts..
is that the positive inotropic effect of enkephalins on cultured chick embryo myocardial cells is correlated with adenylate cyclase stimulation and consequent increases in cyclic AMP
Dose-response Effects of Different Concentrations of Solubilized Human Type I Collagen and the Synthetic Di-peptide Gly-Pro on Migration of Cultured Tumor Cells.. Human Type I Collagen
Gels 4, 8, 12, and 13 contain type I collagen, type III collagen, alI chains, and fibronectin, respectively; each protein was incubated for 120 mim at 37°C with Factor XIII, thrombin,
The recent suggestion that cells from human 15 and calf skin 16 synthesize type I and type III collagen has led to the present investigation, which demonstrates: a that cultured cells
The effect of extracellular matrix ECM proteins such as collagen type I, collagen type IV, gelatin, laminin, fibronectin, Matrigel a mixture of laminin, collagen type IV, heparan
Western blotting and related densitometric analysis of the protein synthesis of α-smooth muscle actin α-SMA, S100A4, type I collagen COL-1 and fibronectin FN in cultured human SSc skin
The production of types I, III, and VI collagen was significantly inhibited in SSc and healthy control dermal fibroblasts without affecting total protein synthesis.. The inhibitory
Abbreviations COL1A2: type II collagen α2 chain; COL2A1: type I collagen α1 chain; COL10A1: type × collagen α1 chain; ECM: extracellular matrix; EDTA: ethylenediaminetetraacetic acid;
Several facts support that the role of liver stellate cells HSC are interrelated with markers arginase-1 Arg-1, cytokine IL-13, extracellular matrix fibronectin FN, and Tissues
B The expression levels of the major extracellular matrix components collagen type-I, collagen type-III, elastin, and fibronectin were lower in pig scar tissues treated with gel/Ad-RLX
Int I De\', BioI 38 X5 98 (1994) 85 Original Article I Developing blood vessels and associated extracellular matrix as substrates for neural crest migration in Japanese quail, Coturnix
Inl I Dn Riol 'H 701 707l1~~~) 701 Origillfll A rlir/f' Guidance of filopodial extension by fibronectin rich extracellular matrix fibrils during avian gastrulation A study using confocal
Inl J UeL Hinl ' I I W 147 (I()()()) 139 Fibronectin rich fibrillar extracellular matrix controls cell migration during amphibian gastrulation JEAN CLAUDE BOUCAUT", KURT E JOHNSON', THIERRY
Inl I De' Hiul B 227 237 t 19X1)) Influence of various extracellular matrix components on the behavior of cultured chick embryo dermal cells JOELLE ROBERT, AN NICK MAUGER and PHILIPPE SENGEL'