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Tiotropium reduces risk of exacerbations irrespective of previous use of inhaled anticholinergics in placebo-controlled clinical trials

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Academic year: 2020

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Figure

Figure 1 study design overview. Patients from 10 pooled trials, receiving tiotropium or placebo, were analyzed according to whether they were receiving inhaled anticholinergics prior to participation in the trial, hence discontinued at trial start, or if they were not receiving inhaled anticholinergics at trial initiation, therefore did not discontinue (not discontinued).Abbreviations: AC, anticholinergic; OD, once daily.
Figure 2 Cumulative incidence estimate (Kaplan–Meier) of the probability of a who discontinued inhaled anticholinergics at randomization; and who were not prescribed inhaled anticholinergics prior to randomization (ie, no discontinuation of inhaled anticho
Table 2 number of patients with at least one exacerbation by discontinuation of anticholinergics

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