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<p>Nanotoxicology of Dendrimers in the Mammalian Heart: ex vivo and in vivo Administration of G6 PAMAM Nanoparticles Impairs Recovery of Cardiac Function Following Ischemia-Reperfusion Injury</p>

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Figure

Figure 1 Schematic representation showing the experimental protocols used for the study (n=6 per group)
Figure 2 The dose-dependent effects of ex vivo direct administration of G6 PAMAM (0.1, 1.0 and 2 µg/mL) on recovery of cardiac function in isolated non-diabetic heartsfollowing I/R injury (n=6)
Table 1 Effects of Ischemia Reperfusion, G6 PAMAM and PPC on Left Ventricle Contractility
Figure 3 The effect of chronic, repeated in vivo administration of G6 PAMAM on recovery of cardiac function following I/R injury in normal and diabetic hearts (n=6).*P<0.01 compared to the respective control.Abbreviations:Recovery of the heart functions: (
+2

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