Calendar of Events
*New to this month’s Calendar of Events. February 1–4, 2009American Society for Parenteral and Enteral Nutrition (ASPEN) Clinical Nutrition Week, New Orleans, LA. Internet: http://www. nutritioncare.org/ClinicalNutritionWeek/.
March 10–14, 2009
ASN co-sponsors the American Heart Association (AHA) Nutrition, Physical Activity and Metabolism (NPAM) Joint Councils Conference, Palm Harbor, FL. Internet: http://www.americanheart.org/presenter. jhtml?identifier-3056462.
March 12–15, 2009
American Medical Student Association (AMSA) 59th Annual Con-vention, Arlington, VA. Internet: http://www.amsa.org/conv/.
March 25–26, 2009*
Wellness 09—At the Forefront of Food and Health, Rosemont, IL. Sponsored by Institute of Food Technologists. CME credit avail-ability: 11 CPEUs from the Commission on the Dietetic Registra-tion of the American Dietetic AssociaRegistra-tion. Internet: http:// www.ift.org/ftpc.
April 1–3, 2009
3rd International IUPAC Symposium on Trace Elements in Food (TEF-3), Rome, Italy. Organized by the Istituto Superiore di Sanita`. For further information, please contact the Administrative Secretariat, FASI srl. Phone: 39 06 9760 5610. Fax: 39 06 9760 5650. E-mail: iupac2009@fasiweb.com. Internet: http:// www.tef3-2009.it.
April 18–22, 2009
ASN Scientific Sessions and Annual Meeting in conjuction with Experimental Biology (EB), New Orleans, LA. E-mail: eb@faseb. org.
May 8–12, 2009*
American Association of Immunologists (AAI) 96th Annual Meet-ing, Seattle, WA. Internet: http://www.immunology2009.org.
June 1–5, 2009*
ODS Dietary Supplement Research Practicum, Bethesda, MD. For further information, please contact Re´gine Laroche, Practicum Co-ordinator, Office of Dietary Supplements, National Institutes of Health, 6100 Executive Blvd., MSC 7517, Suite 3B01, Bethesda, MD 20892-7517. Phone: 301-435-2920. Fax: 301-480-1845. E-mail: rl161k@nih.gov. Internet: http://dietary-supplements.info. nih.gov.
June 9–11, 2009
Food and Function, 2009, Zilina, Slovakia. Internet: http://www. foodandfunction.com.
August 3–7, 2009
11th International Congress on Amino Acids, Peptides and Pro-teins, Vienna, Austria. Deadline for abstracts is March 31, 2009. For further information, please contact either Prof Gert Lubec (scientific inquiries) at gert.lubec@meduniwien.ac.at. or Robert Mostogl (administrative inquiries), Department of Pediatrics, Medical University of Vienna, Waehringer Guertel 18-20, A 1090 Vienna, Austria. Fax: 431 40400 6065. E-mail: robert. mostoegl@meduniwien.ac.at. Internet: http://www.meduniwien. ac.at/ICAAP09/.
October 4–9, 2009
International Union of Nutritional Sciences (IUNS) 19th International Congress on Nutrition, Bangkok, Thailand. For further information, please contact the Congress Secretariat at AsiaCongress Events Co, Ltd, 10 Soi Lasalle 56, Sukhumvit Road, Bangna, Bangkok 10260, Thailand. Phone: 66 2 748 7881. Fax: 66 2 748 7880. E-mail: icn2009@asiacongress.com. Internet: http://www.icn2009.com/.
Founded in 1928, the American Society for
Nutrition (ASN) is the preeminent professional
organization of nutrition research scientists
throughout the world. ASN members are active
researchers and key policy makers from major
academic, government and corporate settings.
ASN, a constituent society of the Federation of
American Societies for Experimental Biology
(FASEB) and a sponsor of Experimental Biology,
is the authoritative voice on nutrition.
Meetings
t"4/IPMETJUTZFBSMZ4DJFOUJöD4FTTJPOTBOE"OOVBM.FFUJOHJO conjunction with Experimental Biology, a multi-society, interdisciplinary meeting featuring plenary and award lectures, symposia, oral and QPTUFSTFTTJPOT DBSFFSTFSWJDFT BOEFYIJCJUTPGTDJFOUJöDFRVJQNFOU supplies and publications.
t4QFDJBMJ[FE"4/DPOGFSFODFTBSFIFMEUISPVHIPVUUIFZFBSUIBUGPDVT on designated areas of nutrition research and practice.
t*OBEEJUJPOUPUIF4DJFOUJöD4FTTJPOTBOE"OOVBM.FFUJOHBOEPUIFS ASN conferences, ASN joins with other societies to co-sponsor TDJFOUJöDQSPHSBNNJOHPOWBSJPVTUPQJDBMJTTVFT
t.FNCFSTSFDFJWF%*4$06/5&% registration rates to all ASN meetings! Education and Professional Development
t"4/JTDPOUJOVPVTMZFOIBODJOHJUTQSPGFTTJPOBMEFWFMPQNFOUQSPHSBNTGPS nutrition professionals who are members or associate members of ASN. t.FNCFSTALWAYS receive discounted rates on conferences, meetings, resources and other materials that are delivered in person or online! t"4/PòFSTNBOZPQQPSUVOJUJFTGPSOFUXPSLJOH JODMVEJOHUISFF $PVODJMT*OUFSOBUJPOBM/VUSJUJPO .FEJDBM/VUSJUJPO BOE Nutritional Sciences. t.FNCFSTBSFBMTPFMJHJCMFUPKPJOPOFPGUIF3FTFBSDI*OUFSFTU 4FDUJPOT 3*45IF3*4BSFDPNNVOJUJFTEFTJHOFEUPQSPWJEFB NFDIBOJTNGPSUPQJDTQFDJöDEJTDVTTJPOSFHBSEJOHOVUSJUJPOSFTFBSDI and practice. t"4/NFNCFSTDBOBMTPFBSO$POUJOVJOH.FEJDBM&EVDBUJPO $.& DSFEJUT BOECFOFöUGSPNOVNFSPVTJOUFSJOEVTUSZQBSUOFSTIJQT t"4/BOOVBMMZBENJOJTUFSTPWFSUXFOUZ"8"3%4 BOEGSFRVFOUMZ administers travel (3"/54 to assist members in attending select meetings.
Publications
t"4/QVCMJTIFTUXPKPVSOBMT The American Journal of Clinical Nutrition (AJCN) and The Journal of Nutrition (JN).
t"+$/JTUIFIJHIFTUSBOLFEQFFSSFWJFXFEKPVSOBMJOOVUSJUJPOBOE EJFUFUJDT*OQVCMJDBUJPOTJODF "+$/QVCMJTIFTUIFMBUFTUöOEJOHTJO CBTJDBOEDMJOJDBMTUVEJFTSFMFWBOUUPIVNBOOVUSJUJPO t+/ QVCMJTIFETJODF XBTUIFöSTUKPVSOBMEFEJDBUFEUPQVCMJTIJOH PSJHJOBM QFFSSFWJFXFESFTFBSDIJOBMMBSFBTPGOVUSJUJPO5IFKPVSOBM QSPWJEFTUIFMBUFTUSFTFBSDIPOUIFCSPBETQFDUSVNPGUPQJDTPGWJUBM JOUFSFTUUPBMMJOUIFOVUSJUJPOTFDUPS
t.FNCFSTSFDFJWF'3&& online access to #05) journals, and discounted QSJOUTVCTDSJQUJPOSBUFT"4/NFNCFSTBMTPCFOFöUGSPNXBJWFE submission fees for AJCN and JN.
t.FNCFSTSFDFJWFUIFRVBSUFSMZOFXTMFUUFS/VUSJUJPO/PUFT and a monthly electronic newsletter.
t"4/NFNCFSTBSFFMJHJCMFGPSEJTDPVOUFETVCTDSJQUJPOTGPSUIFFASEB Journal. Public Affairs
t"4/TFSWFTBTUIFWPJDFGPSDPOUJOVFETVQQPSUBOEBQQMJDBUJPOPGCBTJD and clinical nutrition research through federal government advocacy and education.
t"4/TQVCMJDQPMJDZBOEQVCMJDJOGPSNBUJPOFòPSUTBSFTVQQPSUFECZ a cadre of expert spokespeople who communicate with the media on issues related to nutrition science.
t.FNCFSTSFDFJWFB'3&&twice-monthly public policy e-newsletter, with timely updates on relevant congressional and regulatory activities, grant opportunities, and information regarding government boards and advisory committees nominations.
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Advancing Nutrition Research and Practice Through...
The American Journal of Clinical Nutrition (ISSN 0002-9165) is a publica-tion of the American Society for Nutripublica-tion, 9650 Rockville Pike, Bethesda, MD 20814-3998 USA. The Journal is published monthly with two volumes per year. The primary focus of the Journal is the publication of basic and clinical studies relevant to human nutrition. To read the Information for Authors or to submit a manuscript, please visit WWW.AJCN.ORG. All rights reserved. © 2009 by the American Society for Nutrition. The contents of this publication may not be reproduced in whole or part without consent of the copyright owner. When an abstract appears at the beginning of an article, however, it may be reproduced or translated for noncommer-cial purposes without specific permission, provided the original citation is included. The table of contents and cover also may be reproduced or trans-lated for noncommercial purposes without specific permission.
Statements made and opinions expressed in Original Research Communica-tions, Letters to the Editor, Editorials, Book Reviews, and certain other spe-cial articles appearing in this Journal represent the views of the authors and do not necessarily reflect the position of the American Society for Nutrition. Subscription Services:ASN member: print subscription $40; nonmember personal: print + online $200, online-only $175. Institutional: print + online $490, online-only $475. Student: online-only $60. Contact the subscription office for international and multi-site rates (journal@nutrition.org). Subscription year 2009 January–December (institutions); member and nonmember personal subscriptions begin when the order is processed and continue for 12 months. An order form is available at http://www.ajcn.org/ subscriptions/Orderfrm09.pdf. Periodicals postage paid at Bethesda, MD, and additional mailing offices.
Issue replacement policy:Claims for non-receipt of an issue must be made within 90 days of the issue cover date. Up to two issues will be re-placed free of charge during a subscription period. Replacement requests should be sent to claims@faseb.org or faxed to 301-634-7099.
Change of address, phone, fax, and e-mail:Fax changes to 301-634-7099 or mail to The American Journal of Clinical Nutrition, 9650 Rockville Pike L-3503, Bethesda, MD 20814. Include the old address label or your customer ID.
Advertising Representative:FASEB AdNet, 9650 Rockville Pike, Be-thesda, MD 20814-3998. Phone: (800) 43-FASEB, ext 7157. Fax: (301) 634-7153. Although the American Society for Nutrition does not endorse any commercial enterprise, advertisements are welcomed; guidelines for advertisements can be found at http://www.ajcn.org/misc/advert.shtml. Composition and Printing Services: Dartmouth Journal Services, Pilgrim 5, Suite 5, 5 Pilgrim Park Road, Waterbury, VT 05676. E-mail: ajcn@dartmouthjournals.com.
Postmaster:Send address changes to The American Journal of Clinical Nutrition, 9650 Rockville Pike, L-3503, Bethesda, MD 20814-3998. Be sure to include a copy of the old address label.
Editor-in-Chief Dennis M Bier, MD
Assistant Editor D’Ann Finley, PhD
Associate Editors
Steven A Abrams, MD Naomi K Fukagawa, MD, PhD David H Alpers, MD David M Klurfeld, PhD Barbara A Bowman, PhD Eric B Rimm, ScD Paul M Coates, PhD Frank M Sacks, MD
Editorial Board Lawrence Barker, PhD Nancy F Butte, PhD Susan E Carlson, PhD Laura E Caulfield, PhD Peter M Clifton, MD, PhD Ann M Coulston, MS, RD Richard J Deckelbaum, MD Susan J Fairweather-Tait, PhD, DSc Keith N Frayn, ScD, PhD Dympna Gallagher, EdD Rosalind S Gibson, PhD Peter J Havel, PhD, DVM Robert P Heaney, MD Janet C King, PhD
David J Jenkins, MD, PhD, DSc
Editorial Office:The American Journal of Clinical Nutrition, USDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030-2600. Phone: (713) 798-7022. Fax: (713) 798-7046. E-mail: dbier@nutrition.org. For ques-tions about manuscript submission and status, please e-mail ajcnsubmit@ nutrition.org, telephone (530) 752-8363, or fax (530) 752-8371.
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Managing Editor Darren T Early Administrative Assistants Sharon Lovejoy Deborah Johansson Gordon L Jensen, MD, PhD Ishwarlal (Kenny) Jialal, MD, PhD Simin Nikbin Meydani, DVM, PhD Jose M Ordovas, PhD Stephen D Phinney, MD, PhD Sally P Stabler, MD Meir J Stampfer, MD Patrick J Stover, PhD Maret G Traber, PhD Richard P Troiano, PhD Petra Verhoef, PhD Craig H Warden, PhD Walter C Willett, MD, DrPH Richard J Wood, PhD Susan Z Yanovski, MD
The American Journal of
CLINICAL NUTRITION
A Publication of the American Society for Nutrition
The American Society for Nutrition
SUSTAINING MEMBERS
The American Society for Nutrition is pleased to acknowledge the generous support of these organizations. Abbott Laboratories
The Almond Board of California The Beef Checkoff
Cadbury Adams Americas Confectionery Campbell Soup Company
ConAgra Foods, Inc The Dannon Company, Inc DSM Nutritional Products, Inc Eli Lilly and Company General Mills
Gerber Products Company
GlaxoSmithKline Consumer Healthcare Herbalife
Kellogg Company Kraft Foods, Inc Mars, Inc
Martek Biosciences Corp McCormick Science Institute McNeil Nutritionals Mead Johnson Nutritionals Monsanto Company National Dairy Council
Nestle Nutrition Institute of Nestlé USA Pepsico
Pharmanex
POM Wonderful, LLC
The Procter & Gamble Company The Sugar Association, Inc Unilever Bestfoods Wm Wrigley Jr Company Wyeth Consumer Healthcare Wyeth Nutrition
AMERICAN SOCIETY FOR NUTRITION EXECUTIVE BOARD 2008–2009 President James O Hill, PhD Vice President John L Beard, PhD Vice President-Elect Robert M Russell, MD Past President Joanne Lupton, PhD Secretary
Teresa Ann Davis, PhD Treasurer
Mary Frances Picciano, PhD
MC Chair Thomas Ziegler, MD IC Chair Laura Caulfield, PhD NSC Chair Susan Hutson, PhD RIS Director Cindy Davis, PhD Executive Officer John E Courtney, PhD FACULTY POSITION DIVISION OF NUTRITION
Georgia State University Atlanta, GA
POSITION: Division Head (Associate Professor/Full Professor) position in the Division of Nutrition.
QUALIFICATIONS: Must be a Registered Dietitian (RD) with eligibility for licensure in the state of Georgia. Ph.D. is required with at least one graduate degree in the area of Nutrition, Dietetics, Food Science or related area.
RESPONSIBILITIES: Managing the general operation of the Division of Nutrition and will report to the Director of the School of Health Professions. Other responsibilities include teaching in the primary area of expertise, research, supervision of graduate student projects, and service to the university and professional communities. DEADLINE FOR APPLICATIONS: August 2009.
For more information on the Division of Nutrition, visit the website at http://chhs.gsu.edu/nutrition/.
Submit a letter of application, summarizing your experience and qualifications; curriculum vitae and two recent publications demonstrating your current area of research interest. Electronic applications: Sonda Abernathy at
healthprofessions@gsu.edu. Include Nutrition Search Committee
(Log# 10-029) in subject line.
Paper applications: Sonda Abernathy, Nutrition Search Committee
(Log# 10-029), School of Health Professions, Georgia State
University, PO Box 4019, Atlanta, GA 30302-4019.
Georgia State University is an Equal Opportunity/Affirmative Action university and accommodates individuals with disabilities. All applicants must comply with the immigration Reform and Control Act. Women and minorities are strongly encouraged to apply.
Need to promote open positions,
fellowship opportunities, programs,
or conferences in nutrition?
Advertise in the publications of the American Society for Nutrition (ASN). The ASN publications, The Journal of Nutrition (JN) and The American Journal of Clinical Nutrition (AJCN) are a perfect way to advertise to research scientists, physicians, and registered dieticians in any area of nutrition. JN is the first journal created solely for publishing nutrition research and AJCN is the highest ranked, peer reviewed jour-nal in nutrition and dietetics. Some issues are featured at high attendance meetings like the American Dietetic Association and Experimental Biology annual meetings. Product and recruitment advertising are accepted. Email ads and online ad design are availalbe. New online advertising opportunities are on the ASN website and eNewsletter.
C
ONTACTFASEB AdNet at 301-634-7156 or email
adnet@faseb.org for ad estimate. View ASN rate
card
and full media kit at www.faseb.org/adnet.
University of Kansas, Center for
Physical Activity and Weight
Management
The Center for Physical Activity, and Weight
Management, has locations in Lawrence and
Kansas City, and supports research, training, and
outreach programs for weight loss and weight
maintenance for both children and adults. The
Center is currently following over 500 participants
enrolled in the Weight Control Research Project that
is designed to provide weight loss and weight
maintenance for adults. We also have 5 funded
projects from the National Institutes of Health to
investigate exercise, nutrition, prevention of obesity
and weight loss in both adults and children and
several industry sponsored programs that
investigate nutritional manipulations on energy
intake and body composition. The Center currently
has the following positions open: post-doctoral
researchers (00062363), and graduate research
assistants (MS, Ph.D.). Applications are accepted
on an ongoing basis. To apply for the Post Doctoral
Research position please apply on-line with the
University at jobs.ku.edu (position number
00062363). To apply for the Graduate Research
Assistant please email Kim@ku.edu your cover
letter, resume/vita and a list of three professional
references. Posting Details of Duties, Required and
Preferred Qualifications and application procedures
can be found online at www.ebl.ku.edu. Questions?
email Kim@ku.edu. EO/AA.
FEBRUARY 2009 • VOLUME 89 • NUMBER 2
W W W. A J C N . O R G ISSN 0002-9165EDITORIALS
Screening for iron deficiency during early infancy: is it feasible and is it necessary? GR Buchanan
See corresponding article on page 525.
473
Hepcidin compared with prohepcidin: an absorbing story. DM Frazer and GJ Anderson
See corresponding article on page 533.
475
SPECIAL TASK FORCE REPORT
Can a small-changes approach help address the obesity epidemic? A report of the Joint Task Force of the American Society for Nutrition, Institute of Food Technologists, andInternational Food Information Council. JO Hill
477
ORIGINAL RESEARCH COMMUNICATIONS
Cardiovascular disease risk
Effects of a low-salt diet on flow-mediated dilatation
in humans. KM Dickinson et al
485
Nutritional status, dietary intake, and body composition
Aggregate predictions improve accuracy when calculating metabolic variables used to guide treatment.
JCK Wells et al
491
Comparisons of percentage body fat, body mass index, waist circumference, and waist-stature ratio in adults.
KM Flegal et al
500
Association of 1-y changes in diet pattern with cardiovascular disease risk factors and adipokines: results from the 1-y randomized Oslo Diet and Exercise Study.
DR Jacobs Jr et al
509
Carbohydrate metabolism and diabetes
Association of diet with glycated hemoglobin during intensive treatment of type 1 diabetes in the Diabetes Control and
Complications Trial. LM Delahanty et al
518
Vitamins, minerals, and phytochemicals
Iron supplementation of breastfed infants from an early age. EE Ziegler et al
See corresponding editorial on page 473.
525
Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young women. MF Young et al
See corresponding editorial on page 475.
533
Optimization of a phytase-containing micronutrient powder with low amounts of highly bioavailable iron for in-home
fortification of complementary foods. B Troesch et al
539
Growth, development, and pediatrics
Folate concentrations in pediatric patients with newly
diagnosed inflammatory bowel disease. MB Heyman et al
545
Intergenerational influences on childhood body mass index: the effect of parental body mass index trajectories. L Li et al
551
Digestive and liver diseases
Prolonged saturated fat–induced, glucose-dependent insulinotropic polypeptide elevation is associated with adipokine imbalance and liver injury in nonalcoholic steatohepatitis: dysregulated enteroadipocyte axis as a
novel feature of fatty liver. G Musso et al
558
Cancer
Glycemic index, glycemic load, and risk of digestive tract neoplasms: a systematic review and meta-analysis.
HG Mulholland et al
568
Prospective cohort study of soy food intake and
colorectal cancer risk in women. G Yang et al
577
Vitamin E intake, ␣-tocopherol status, and pancreatic cancer in a cohort of male smokers.
RZ Stolzenberg-Solomon et al
584
AIDS and other wasting syndromes
Reduced production of sulfated glycosaminoglycans occurs in Zambian children with kwashiorkor but not marasmus.
B Amadi et al
592
Aging
Body mass index over the adult life course and cognition
in late midlife: the Whitehall II Cohort Study. S Sabia et al
601
Protein supplementation before and after exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men. LB Verdijk et al
608
Continued on Table of Contents inside
SUPPLEMENTS
Methyl Donors, Iodine, and Docosahexaenoic Acid
(DHA)—Is Maternal Supplementation Beneficial?
657S
Is It Time for Mandatory Vitamin B-12 Fortification in Flour?689S
A Publication of the American Society
for Nutrition
FEBRUAR
Y
2009
The American Journal of CLINICAL NUTRITION
VOLUME 89
NUMBER 2
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AGES