• No results found

The integrative epigenomic-transcriptomic landscape of ER positive breast cancer

N/A
N/A
Protected

Academic year: 2020

Share "The integrative epigenomic-transcriptomic landscape of ER positive breast cancer"

Copied!
16
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Fig. 1 The FEM algorithm and examples of FEM modules in ER+ breast cancer. a The FEM algorithm first uses gene-centred statistics ofdifferential DNA methylation, tg(D) and differential mRNA expression, tg(R), here between normal and ER+ breast cancer, to w
Fig. 2 Validation of FEM module gene t-statistics. For each FEM module, a scatterplot of t-statistics of differential DNAm (red) and mRNAexpression (blue) in discovery TCGA set (x-axis) against the corresponding statistics in the validation set (y-axis)
Table 2 GSEA on FEM modules revealed strong enrichment oftwo FEMs with seed genes CAV1 and FSTL1, respectively
Fig. 4 FEM modules discriminate normal, luminal-A and luminal-B breast cancers. a Boxplots of FEM deviation scores for the FSTL1 and CAV1FEMs, stratified according to normal, luminal-A and luminal-B breast cancers
+4

References

Related documents

The present work was conducted to study the performance of prepared mono and bimetallic catalyst of Co and Ni active metals supported by activated carbon on the Fischer-Tropsch

The strict and modified Westphalian narratives capture the role that treaty and customary international law must play in solving the problem, but they may

127, 132 (1948) (finding that no invention existed when several species of bacteria were mixed in a beneficial way). The plant could possibly obtain protection through the PVPA,

• Discuss the types of positions available in the health informatics setting. • Discover the importance of

For vehicle service contracts, exposure bases are somewhat unique in that the exposure base used to price and rate the coverage (Miles/Time) is not the exposure base that has been

Using Open Geographic Data to Generate Natural Language Descriptions for Hydrological Sensor Networks.. Martin Molina *, Javier Sanchez-Soriano and

Then, we estimate the incumbency effect for the direct district candidates in German federal and state elections using a regression discontinuity design (RDD).. When studying