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Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression

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Figure

Figure 1 CNTF is repressed by ECM and specific αvβ5 integrin and neuronal Thy-1 ligand
Table 1 Process to define which integrins repress CNTF
Figure 2 FAK inhibition induces CNTF expressionchange compared to controls and are shown as average +/ in vitro
Figure 3 A specific intracellular FAK-JNK signaling pathwayrepresses CNTF. A) Incubation of C6 cells with inhibitors of JNK,but not p38 or ERK, for 4 hours, increases CNTF mRNA compared tovehicle controls (Ctrl)
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